Some can be used alone or along with a statin to help patients reach their cholesterol targets. By far, the statins are the most effective at lowering LDL, which is the primary target of treatment. The first approved drug … By Jen Christensen, CNN (CNN) -- The US Food and Drug Administration on Friday approved a drug to treat high cholesterol that works differently than statins, according to Esperion … They lower LDL by 18 to 55 percent. While Statins primarily lower cholesterol by preventing its production in the liver, a new class of drug called cholesterol absorption inhibitors lowers cholesterol by preventing it from being absorbed in the intestine. But a small percentage of people don’t do well with statins, meaning the drugs … For years, statins have been the drug of choice when it comes to treating high cholesterol, and that remains the case today.That means they’re usually the first medication providers will consider when recommending a cholesterol-lowering treatment. Non-statin cholesterol-lowering medicines work in different ways. WASHINGTON - The FDA this month approved the first non-statin oral medication for high cholesterol in almost two decades, giving patients and doctors another weapon against heart disease, … The non-statin cholesterol-lowering medications are also effective at … “Our goal in treating cholesterol is to get it as low as possible based on the patient's individual risk, so it's not uncommon to use two medications …

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